Molecular decomposition of complex clinical phenotypes using biologically structured analysis of microarray data

URN to cite this document:: urn:nbn:de:bvb:355-epub-329516
DOI to cite this document:: 10.5283/epub.32951

Lottaz, Claudio ; Spang, Rainer

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Date of publication of this fulltext: 04 Dec 2015 09:26

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Abstract

MOTIVATION: Today, the characterization of clinical phenotypes by gene-expression patterns is widely used in clinical research. If the investigated phenotype is complex from the molecular point of view, new challenges arise and these have not been addressed systematically. For instance, the same clinical phenotype can be caused by various molecular disorders, such that one observes different ...