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A co-culture model of fibroblasts and adipose tissue-derived stem cells reveals new insights into impaired wound healing after radiotherapy

Haubner, Frank, Mutscher, Dominique, Pohl, Fabian, Schreml, Stephan, Prantl, Lukas and Gassner, Holger G. (2015) A co-culture model of fibroblasts and adipose tissue-derived stem cells reveals new insights into impaired wound healing after radiotherapy. International Journal of Molecular Sciences 2015 (16), pp. 25947-25958.

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Date of publication of this fulltext: 02 Dec 2015 16:06

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Other URL: http://www.mdpi.com/1422-0067/16/11/25935


Abstract

External radiation seems to be associated with increased amounts of cytokines and other cellular modulators. Impaired microcirculation and fibrosis are examples of typical long term damage caused by radiotherapy. Adipose tissue-derived stem cells (ASC) are discussed to enhance wound healing, but their role in wounds due to radiotherapy is poorly understood. Normal human fibroblasts (NHF) and ASCs ...

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Item type:Article
Date:29 October 2015
Institutions:Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3390/ijms161125935DOI
Keywords:external radiation; fibroblasts; adipose derived stem cells; matrix metalloproteinases; tissue inhibitors of matrix metalloproteinases
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:32965
Owner only: item control page

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