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Ibuprofen and Diclofenac Restrict Migration and Proliferation of Human Glioma Cells by Distinct Molecular Mechanisms

Hau, Peter, Leidgens, Verena, Seliger, Corinna, Jachnik, Birgit, Welz, Tobias, Leukel, Petra, Vollmann-Zwerenz, Arabel, Bogdahn, Ulrich, Kreutz, Marina and Grauer, Oliver M. (2015) Ibuprofen and Diclofenac Restrict Migration and Proliferation of Human Glioma Cells by Distinct Molecular Mechanisms. PLoS ONE 10 (10), e0140613.

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Date of publication of this fulltext: 04 Dec 2015 11:38

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Other URL: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140613


Abstract

Background Non-steroidal anti-inflammatory drugs (NSAIDs) have been associated with anti-tumorigenic effects in different tumor entities. For glioma, research has generally focused on diclofenac; however data on other NSAIDs, such as ibuprofen, is limited. Therefore, we performed a comprehensive investigation of the cellular, molecular, and metabolic effects of ibuprofen and diclofenac on human ...

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Item type:Article
Date:20 October 2015
Institutions:Medicine > Lehrstuhl für Neurologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0140613DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:32997
Owner only: item control page

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