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Reactivity of rat bone marrow-derived macrophages to neurotransmitter stimulation in the context of collagen II-induced arthritis

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Grässel, Susanne ; Mutscher, Dominique ; Göttl, Claudia ; Vogel, Mandy ; Grifka, Joachim ; Straub, Rainer H.
Date of publication of this fulltext: 10 Dec 2015 16:41


Introduction Numerous observations indicate that rheumatoid arthritis (RA) has a bone marrow component. In parallel, local synovial changes depend on neuronal components of the peripheral sympathetic nervous system. Here, we wanted to analyze whether collagen II-induced arthritis (CIA) has an impact on number, adhesion, apoptosis, and proliferation of the macrophage subset of bone marrow cells ...


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