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Cannabinoid-based drugs targeting CB 1 and TRPV1, the sympathetic nervous system, and arthritis

Lowin, Torsten and Straub, Rainer H. (2015) Cannabinoid-based drugs targeting CB 1 and TRPV1, the sympathetic nervous system, and arthritis. Arthritis Research & Therapy 17 (226), pp. 1-13.

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Date of publication of this fulltext: 11 Dec 2015 14:09

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Other URL: http://www.arthritis-research.com/content/17/1/226


Abstract

Chronic inflammation in rheumatoid arthritis (RA) is accompanied by activation of the sympathetic nervous system, which can support the immune system to perpetuate inflammation. Several animal models of arthritis already demonstrated a profound influence of adrenergic signaling on the course of RA. Peripheral norepinephrine release from sympathetic terminals is controlled by cannabinoid receptor ...

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Item type:Article
Date:6 September 2015
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1186/s13075-015-0743-xDOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:33044
Owner only: item control page

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