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Activating enhancer binding protein 2 epsilon (AP-2ε)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development

Bosserhoff, Anja-Katrin, Niebler, Stephan, Schubert, Thomas and Hunziker, Ernst B. (2015) Activating enhancer binding protein 2 epsilon (AP-2ε)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development. Arthritis Research & Therapy 17 (119), pp. 1-16.

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Date of publication of this fulltext: 15 Dec 2015 10:25

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Other URL: http://www.arthritis-research.com/content/17/1/119


Abstract

Introduction The transcription factor activating enhancer binding protein 2 epsilon (AP-2ε) was recently shown to be expressed during chondrogenesis as well as in articular chondrocytes of humans and mice. Furthermore, expression of AP-2ε was found to be upregulated in affected cartilage of patients with osteoarthritis (OA). Despite these findings, adult mice deficient for AP-2ε (Tfap2e−/−) do ...

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Item type:Article
Date:12 March 2015
Institutions:Medicine > Lehrstuhl für Pathologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1186/s13075-015-0648-8DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:33065
Owner only: item control page

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