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The Diels-Alder reaction: A powerful tool for the design of drug delivery systems and biomaterials

Gregoritza, Manuel and Brandl, Ferdinand (2015) The Diels-Alder reaction: A powerful tool for the design of drug delivery systems and biomaterials. European Journal of Pharmaceutics and Biopharmaceutics 97, Part B, pp. 438-453.

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Abstract

Click reactions have the potential to greatly facilitate the development of drug delivery systems and biomaterials. These reactions proceed under mild conditions, give high yields, and form only inoffensive by-products. The Diels–Alder cycloaddition is one of the click reactions that do not require any metal catalyst; it is one of the most useful reactions in synthetic organic chemistry and ...

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Item type:Article
Date:November 2015
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Identification Number:
ValueType
10.1016/j.ejpb.2015.06.007DOI
Keywords:Diels–Alder reaction; Click chemistry; Drug delivery; Biomaterials; Polymers; Dendrimers; Surface functionalization; Bioconjugation; Nanoparticles; Hydrogels
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:33260
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