Measurement properties of quality of life measurement instruments for infants, children and adolescents with eczema: protocol for a systematic review

URN zum Zitieren dieses Dokuments: urn:nbn:de:bvb:355-epub-335084

Heinl, Daniel, Prinsen, Cecilia A. C., Apfelbacher, Christian J., Drucker, Aaron M., Ofenloch, Robert, Humphreys, Rosemary, Sach, Tracey und Flohr, Carsten (2016) Measurement properties of quality of life measurement instruments for infants, children and adolescents with eczema: protocol for a systematic review. Systematic Reviews 5 (25), S. 1-10.

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Andere URL zum Volltext: http://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-016-0202-z

Zusammenfassung

Zusammenfassung

Background
Eczema is a common chronic or chronically relapsing, inflammatory skin disease that exerts a substantial negative impact on quality of life (QoL). The Harmonising Outcome Measures for Eczema (HOME) initiative has used a consensus-based process which identified QoL as one of the four core outcome domains to be assessed in all eczema clinical trials. A number of measurement instruments exist to measure QoL in infants, children, and adolescents with eczema, and there is a great variability in both content and quality of the instruments used. Therefore, the objective of the proposed research is to comprehensively and systematically assess the measurement properties of the existing measurement instruments that were developed and/or validated for the measurement of patient-reported QoL in infants, children, and adolescents with eczema.

Methods/design
This study is a systematic review of the measurement properties of patient-reported measures of QoL developed and/or validated for infants, children, and adolescents with eczema. A systematic literature search will be carried out in MEDLINE via PubMed and EMBASE using a selection of relevant search terms. Eligible studies will be primary empirical studies evaluating, describing, or comparing measurement properties of QoL instruments for infants, children, and adolescents with eczema. Two reviewers will independently perform eligibility assessment and data abstraction. Evidence tables will be used to record study characteristics, instrument characteristics, measurement properties, and interpretability. The adequacy of the measurement properties will be assessed using predefined criteria. The COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist will be used to evaluate the methodological quality of included studies. A best evidence synthesis will be undertaken if more than one study has examined a particular measurement property.

Discussion
The proposed systematic review will yield a comprehensive assessment of measurement properties of existing QoL instruments in infants, children, and adolescents with eczema. The results will serve as a basis to recommend a QoL measurement instrument for infants, one for children, and one for adolescents for use in future clinical trials.

Systematic review registration
PROSPERO CRD42015023483

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Dokumentenart:

Artikel

Datum:

9 Februar 2016

Institutionen:

Medizin > Institut für Epidemiologie und Präventivmedizin > Medizinische Soziologie

Projekte:

Open Access Publizieren (DFG)

Identifikationsnummer:

Wert	Typ
10.1186/s13643-016-0202-z	DOI

Stichwörter / Keywords:

Eczema; Atopic dermatitis; Measurement instruments; Health-related quality of life; Quality of life; Validity; Reliability; Responsiveness; Interpretability

Dewey-Dezimal-Klassifikation:

600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin

Status:

Veröffentlicht

Begutachtet:

Ja, diese Version wurde begutachtet

An der Universität Regensburg entstanden:

Eingebracht am:

10 Mrz 2016 12:44

Zuletzt geändert:

08 Mrz 2017 08:40

Dokumenten-ID:

33508

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