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The role of LRRC8A for cellullar volume regulation and apoptosis

URN to cite this document:
urn:nbn:de:bvb:355-epub-335420
DOI to cite this document:
10.5283/epub.33542
Zormpa, Anna
Date of publication of this fulltext: 22 Mar 2016 13:13


Abstract (English)

Volume regulation is a crucial property of all living cells and it contributes to several physiological and pathological procedures. The volume regulated anion channel (VRAC) is involved in volume regulation, more specifically in regulatory volume decrease (RVD), and in volume decrease during apoptosis (apoptotic volume decrease, AVD). The protein LRRC8A (leucin rich repeat protein 8A) has been ...

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Translation of the abstract (German)

Volumenregulation stellt eine überlebenswichtige Eigenschaft aller Zellen dar und spielt bei mehreren physiologischen und pathologischen Vorgängen eine Rolle. Der volumenregulierte Anionen- Kanal (volume regulated anion channel; VRAC) ist an der Volumenregulation, genauer an der regulatorischen Volumenabnahme (regulatory volume decrease; RVD), sowie an der Volumenabnahme während der Apoptose ...

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