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Effects of TNF Receptor Signalling on the the Function of Suppressive Immune Cells

Weber, Sabine (2016) Effects of TNF Receptor Signalling on the the Function of Suppressive Immune Cells. PhD, Universität Regensburg.

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Date of publication of this fulltext: 11 Apr 2016 12:12

Abstract (English)

Unlike conventional immune cells, the main function of regulatory T cells (Treg) and myeloid-derived suppressor cells (MDSC) is not the host defence but the regulation of immune responses. Their dysfunction can lead to a variety of possible harmful effects for the organism. In case of a reduced activity of these suppressive immune cells, a diminished inhibition of autoreactive cells can be seen, ...

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Translation of the abstract (German)

Regulatorische T-Zellen (Treg) und myeloide Suppressorzellen sind Immunzellen, deren Hauptfunktion nicht in der Abwehr von Pathogenen, sondern in der Regulation von Immunantworten liegt. Die Fehlfunktion dieser immunregulatorischen Zellen kann eine Vielzahl von fatalen Folgen haben. Falls die immunregulatorische Funktion geschwächt ist, kann dies zu einer fehlenden Hemmung von autoreaktiven ...

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Export bibliographical data



Item type:Thesis of the University of Regensburg (PhD)
Date:11 April 2016
Referee:Prof. Dr. Daniela Männel
Date of exam:24 February 2016
Institutions:Medicine > Lehrstuhl für Immunologie
Keywords:regulatory T cells; TNF; Stat5; MDSC; ZAP70
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:33567
Owner only: item control page

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