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Molekulare Funktion und Transport von MIA (Melanoma Inhibitory Activity)

Molnar, Matthias (2017) Molekulare Funktion und Transport von MIA (Melanoma Inhibitory Activity). PhD, Universität Regensburg.

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Date of publication of this fulltext: 04 Apr 2017 05:16

Abstract (German)

Zusammenfassung MIA (Melanoma Inhibitory Activity) ist ein wichtiges Protein, das an der Progression und Metastasierung des malignen Melanoms beteiligt ist. MIA wird von Melanomzellen exprimiert und migrationsabhängig am distalen Zellpol sekretiert. Im Extrazellularraum fördert es die Ablösung der Tumorzellen von der Extrazellulären Matrix (Extracellular matrix, ECM) und dadurch die Migration und ...

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Translation of the abstract (English)

Summary MIA (Melanoma Inhibitory Activity) is a very important protein, involved in melanoma progression and metastasis. In melanoma cells, MIA is expressed and migration-associated secreted at the cell rear. In the extracellular space MIA promotes the detachment of tumor cells from the ECM (Extracellular matrix) and thereby increases the migratory and invasive potential of melanoma cells. This ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:4 April 2017
Referee:Prof. Dr. Rainer Deutzmann
Date of exam:4 March 2016
Institutions:Medicine > Lehrstuhl für Pathologie
Keywords:MIA, Funktion, Transport
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:33615
Owner only: item control page

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