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Haertl, Petra ; Treutwein, Marius ; Hautmann, Matthias G. ; Maerz, Manuel ; Pohl, Fabian ; Koelbl, Oliver ; Dobler, Barbara

Total Body Irradiation - an Attachment Free Sweeping Beam Technique

Haertl, Petra, Treutwein, Marius , Hautmann, Matthias G., Maerz, Manuel, Pohl, Fabian, Koelbl, Oliver und Dobler, Barbara (2016) Total Body Irradiation - an Attachment Free Sweeping Beam Technique. Radiation Oncology 11 (81).

Veröffentlichungsdatum dieses Volltextes: 13 Jun 2016 09:20
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.33719


Zusammenfassung

Introduction: A sweeping beam technique for total body irradiation in standard treatment rooms and for standard linear accelerators (linacs) is introduced, which does not require any accessory attached to the linac. Lung shielding is facilitated to reduce the risk of pulmonary toxicity. Additionally, the applicability of a commercial radiotherapy planning system (RTPS) is examined. Material and ...

Introduction: A sweeping beam technique for total body irradiation in standard treatment rooms and for standard linear accelerators (linacs) is introduced, which does not require any accessory attached to the linac. Lung shielding is facilitated to reduce the risk of pulmonary toxicity. Additionally, the applicability of a commercial radiotherapy planning system (RTPS) is examined. Material and Methods: The patient is positioned on a low couch on the floor, the longitudinal axis of the body in the rotational plane of the linac. Eight arc fields and five additional fixed beams are applied to the patient in supine and prone position respectively. The dose distributions were measured in a solid water phantom and in an Alderson phantom. Diode detectors were calibrated for in-vivo dosimetry. The RTPS Oncentra was employed for calculations of the dose distribution. Results: For the cranial 120 cm the longitudinal dose profile in a slab phantom measured with ionization chamber varies between 94 and 107 % of the prescription dose. These values were confirmed by film measurements and RTPS calculations. The transmittance of the lung shields has been determined as a function of the thickness of the absorber material. Measurements in an Alderson phantom and in-vivo dosimetry of the first patients match the calculated dose. Discussion and conclusion: A treatment technique with clinically good dose distributions has been introduced, which can be applied with each standard linac and in standard treatment rooms. Dose calculations were performed with a commercial RTPS and should enable individual dose optimization.



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Details

DokumentenartArtikel
Titel eines Journals oder einer ZeitschriftRadiation Oncology
Verlag:BMC
Ort der Veröffentlichung:LONDON
Band:11
Nummer des Zeitschriftenheftes oder des Kapitels:81
Datum10 Juni 2016
InstitutionenMedizin > Lehrstuhl für Strahlentherapie
Identifikationsnummer
WertTyp
10.1186/s13014-016-0658-yDOI
27287010PubMed-ID
Stichwörter / KeywordsBONE-MARROW-TRANSPLANTATION; STEM-CELL TRANSPLANTATION; INTERSTITIAL PNEUMONITIS; DOSE-RATE; VERIFICATION; TOXICITY; LEUKEMIA; THERAPY; ADULTS; TBI; Total body irradiation; Sweeping beam technique; Lung shielding; Dosimetry; 3D treatment planning
Dewey-Dezimal-Klassifikation600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
StatusVeröffentlicht
BegutachtetJa, diese Version wurde begutachtet
An der Universität Regensburg entstandenJa
URN der UB Regensburgurn:nbn:de:bvb:355-epub-337190
Dokumenten-ID33719

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