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Refining Pathways: A Model Comparison Approach

URN to cite this document:
urn:nbn:de:bvb:355-epub-338701
DOI to cite this document:
10.5283/epub.33870
Moffa, Giusi ; Erdmann, Gerrit ; Voloshanenko, Oksana ; Hundsrucker, Christian ; Sadeh, Mohammad Javad ; Boutros, Michael ; Spang, Rainer
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Date of publication of this fulltext: 16 Jun 2016 07:15



Abstract

Cellular signalling pathways consolidate multiple molecular interactions into working models of signal propagation, amplification, and modulation. They are described and visualized as networks. Adjusting network topologies to experimental data is a key goal of systems biology. While network reconstruction algorithms like nested effects models are well established tools of computational biology, ...

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