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Myeloid-derived Suppressor Cells in Glioblastoma Patients - Phenotype, Function and Clinical Relevance

Dubinski, Daniel (2016) Myeloid-derived Suppressor Cells in Glioblastoma Patients - Phenotype, Function and Clinical Relevance. PhD, Universität Regensburg.

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Date of publication of this fulltext: 21 Jun 2016 11:58

Abstract (English)

Myeloid-derived suppressor cells (MDSCs) comprise a heterogeneous population of myeloid cells that are significantly expanded in cancer patients and are associated with tumor progression. Multicolor flow cytometry was used to study the frequency, phenotype, and function of MDSCs in peripheral blood and freshly resected tumors of 52 participants with primary glioblastoma (GBM). This thesis ...

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Translation of the abstract (German)

Myeloide Suppressorzellen bestehen aus einer heterogenen Zellpopulation, welche bei Tumorpatienten in einer erhöhten Anzahl vorliegen und mit einem Tumorprogress vergesellschaftet sind. Im Rahmen dieser Arbeit erfolgte eine durchflusszytometrische Untersuchung des Phänotypus, der Funktion sowie der Anzahl der myeloiden Suppressorzellen im Blut sowie im Tumorpräparat von 52 Patienten mit der ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:21 June 2016
Referee:PD.Dr.Dr. Oliver Grauer and Prof.Dr. Peter Hau
Date of exam:21 June 2016
Institutions:Medicine > Lehrstuhl für Neurologie
Keywords:glioblastoma, myeloid-derived suppressor cell, T effector memory cell
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:33879
Owner only: item control page

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