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Funktionelle Analyse von Fussel während der Entwicklung des Nervensystems in Drosophila melanogaster

Raß, Mathias (2018) Funktionelle Analyse von Fussel während der Entwicklung des Nervensystems in Drosophila melanogaster. PhD, Universität Regensburg.

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Date of publication of this fulltext: 02 Jan 2018 07:43

Abstract (German)

Das functional Smad suppressing element (fussel) in Drosophila melanogaster gehört zur Ski/Sno-Proteinfamilie, die sich durch eine Ski/Sno-Homologiedomäne und eine Smad4-Bindedomäne auszeichnet. Eine wichtige Funktion dieser Proteine im physiologischen Kontext ist dabei die Inhibierung des TGF-ß-Signalwegs, der in einem breiten Bereich von Entwicklungsprozessen benötigt wird. In vielen ...

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Translation of the abstract (English)

The functional Smad suppressing element (fussel) in Drosophila melanogaster is a member of the Ski/Sno family of proteins, which are characterized by a Ski/Sno homology domain and a Smad4 binding domain. In the physiological context an important function of these proteins is the inhibition of the TGF-ß signaling pathway, which is required in a wide field of different developmental processes. In ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:2 January 2018
Referee:Prof. Dr. Stephan Schneuwly
Date of exam:30 June 2016
Institutions:Biology, Preclinical Medicine > Institut für Zoologie > Entwicklungsbiologie (Prof. Dr. Stephan Schneuwly)
Keywords:Fussel, Ski/Sno Protein, Dpp-Signalweg, Protoonkogen, Drosophila melanogaster,
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:34078
Owner only: item control page

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