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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-342416
- DOI to cite this document:
- 10.5283/epub.34241
Alternative links to fulltext:DOI
Abstract
The proteolytic activity of renin is a key element in the regulation of blood pressure and a main target for inhibitor design. Currently, the activity of renin and its inhibitors is mainly analyzed using radioimmunoassays or FRET-substrates, which both have their limitations. Here, a novel kinetic assay is presented that combines the advantages of a homogeneous proteolytic reaction and a robust ...
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