Abstract
Azabis(oxazolines) prove to be superior ligands for the enantioselective, cobalt(II)-catalyzed conjugate reduction of alpha,beta-unsaturated carbonyl compounds with sodium borohydride. beta-Trisubstituted a,p-unsaturated esters and amides as well as gamma-butenolides are readily converted to their corresponding saturated counterparts with enantioselectivities up to 97% ee.
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