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Safety and efficacy of defibrotide for the treatment of severe hepatic veno-occlusive disease

Richardson, Paul M., Ho, Vincent T., Giralt, Sergio, Arai, Sally, Mineishi, Shin, Cutler, C., Antin, Joseph H. Antin, Stavitzski, N., Niederwieser, N. and Holler, Ernst (2012) Safety and efficacy of defibrotide for the treatment of severe hepatic veno-occlusive disease. Therapeutic Advances in Hematology 3, pp. 253-265.

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Abstract

Hepatic veno-occlusive disease (VOD), also known as sinusoidal obstruction syndrome, is a potentially life-threatening complication of chemotherapeutic conditioning used in preparation for hematopoietic stem-cell transplantation (SCT). VOD may occur in up to 62% of patients undergoing SCT, with onset generally within the first month after SCT. In severe cases, 100-day mortality is in excess of ...

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Item type:Article
Date:2012
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number:
ValueType
10.1177/2040620712441943DOI
Keywords:defibrotide, sinusoidal obstruction syndrome, veno-occlusive disease
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:34451
Owner only: item control page

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