The Chemopreventive Phytochemical Moringin Isolated from Moringa oleifera Seeds Inhibits JAK/STAT Signaling

URN to cite this document:: urn:nbn:de:bvb:355-epub-344545
DOI to cite this document:: 10.5283/epub.34454

Rascle, Anne ; Michl, Carina

; Vivarelli, Fabio ; Weigl, Julia

; De Nicola, Gina Rosalinda ; Canistro, Donatella ; Paolini, Moreno ; Iori, Renato

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Date of publication of this fulltext: 24 Aug 2016 14:51

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Abstract

Sulforaphane (SFN) and moringin (GMG-ITC) are edible isothiocyanates present as glucosinolate precursors in cruciferous vegetables and in the plant Moringa oleifera respectively, and recognized for their chemopreventive and medicinal properties. In contrast to the well-studied SFN, little is known about the molecular pathways targeted by GMG-ITC. We investigated the ability of GMG-ITC to inhibit ...