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The Chemopreventive Phytochemical Moringin Isolated from Moringa oleifera Seeds Inhibits JAK/STAT Signaling

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Rascle, Anne ; Michl, Carina ; Vivarelli, Fabio ; Weigl, Julia ; De Nicola, Gina Rosalinda ; Canistro, Donatella ; Paolini, Moreno ; Iori, Renato
Date of publication of this fulltext: 24 Aug 2016 14:51


Sulforaphane (SFN) and moringin (GMG-ITC) are edible isothiocyanates present as glucosinolate precursors in cruciferous vegetables and in the plant Moringa oleifera respectively, and recognized for their chemopreventive and medicinal properties. In contrast to the well-studied SFN, little is known about the molecular pathways targeted by GMG-ITC. We investigated the ability of GMG-ITC to inhibit ...


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