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Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice

Männel, Daniela N., Schmidt, Dominic, Peterlik, Daniel, Reber, Stefan Oskar and Lechner, Anja (2016) Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice. PLoS ONE 11 (7), e0159059.

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Date of publication of this fulltext: 25 Aug 2016 09:07

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Other URL: http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0159059


Abstract

To study the impact of psychosocial stress on the immune system, male mice were subjected to chronic subordinate colony housing (CSC), a preclinically validated mouse model for chronic psychosocial stress. CSC substantially affected the cell composition of the bone marrow, blood, and spleen by inducing myelopoiesis and enhancing the frequency of regulatory T cells in the CD4 population. Expansion ...

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Item type:Article
Date:8 July 2016
Institutions:Medicine > Lehrstuhl für Immunologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0159059DOI
Article-ID: e0159059Other
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:34471
Owner only: item control page

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