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Improved Synthesis of Aza-bis(oxazoline) Ligands

Werner, Heiko ; Vicha, Robert ; Gissibl, Anja ; Reiser, Oliver



Abstract

A straightforward synthesis of chiral aza-bis(oxazoline) (Azabox) ligands from commercially available amino alcohols is described. The new protocol allows access to previously reported Azabox ligands in considerably improved yields but also to new derivatives, including non-C2-symmetrical ones.


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