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Rezeptoren für B cell Activating Factor of the Tumor Necrosis Factor Family (BAFF) auf Synovialen Fibroblasten - Vergleichende Studie zwischen Rheumatoider Arthritis und Osteoarthrose

Anssar, Tareq Marius (2016) Rezeptoren für B cell Activating Factor of the Tumor Necrosis Factor Family (BAFF) auf Synovialen Fibroblasten - Vergleichende Studie zwischen Rheumatoider Arthritis und Osteoarthrose. PhD, Universität Regensburg.

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Date of publication of this fulltext: 05 Sep 2016 09:20

Abstract (German)

In der Pathogenese der rheumatoiden Arthritis (RA) nehmen synoviale Fibroblasten (SF) eine zentrale Rolle ein. Sie sind bedeutend für die Regulation anderer Zellen, die Aufrechterhaltung des proinflammatorischen Milieus und die ablaufende Gelenkdestruktion. Im Serum von RA-Patienten konnten erhöhte BAFF- und APRIL-Spiegel nachgewiesen werden. Unzureichend untersucht ist bislang das Zusammenspiel ...

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Translation of the abstract (English)

Synovial Fibroblasts (SF) play a central role in the pathogenesis of rheumatoid arthritis (RA). They are crucial for the regulation of other cells, the maintenance of a proinflammatory environment and bone destruction. Elevated levels of BAFF and APRIL were detected in the serum of RA patients. So far, interaction between the ligands of the BAFF/APRIL system and SF has not been examined ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:5 September 2016
Referee:Prof. Dr. Georg Pongratz
Date of exam:30 August 2016
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Keywords:BAFF, BAFF-Rezeptor, TACI, BCMA, Synoviale Fibroblasten, Rheumatoide Arthritis, RA
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:34504
Owner only: item control page

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