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Behavioral auditory thresholds and loss of ribbon synapses at inner hair cells in aged gerbils

Gleich, Otto ; Semmler, Philipp ; Strutz, Jürgen


The potential contribution of auditory synaptopathy to age dependent hearing loss was studied in groups of young and old gerbils. The analysis of the number of inner hair cell ribbon synapses in aged gerbils (37.9 +/- 3.3 months of age) revealed only a relatively small (11-17%) loss in the basal two thirds of the cochlea, while a more pronounced reduction was identified towards the apex (almost ...


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