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Neuropeptide S alters anxiety, but not depression-like behaviour in Flinders Sensitive Line rats: a genetic animal model of depression

Wegener, G., Finger, B., Elfving, B., Keller, K., Liebenberg, N., Fischer, C.W., Singewald, N., Slattery, David A., Neumann, Inga D. and Mathé, A.A. (2012) Neuropeptide S alters anxiety, but not depression-like behaviour in Flinders Sensitive Line rats: a genetic animal model of depression. International Journal of Neuropsychopharmacology 15, pp. 375-387.

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Abstract

Neuropeptide S (NPS) and its receptor (NPSR) have been implicated in the mediation of anxiolytic-like behaviour in rodents. However, little knowledge is available regarding the NPS system in depression-related behaviours, and whether NPS also exerts anxiolytic effects in an animal model of psychopathology. Therefore, the aim of this work was to characterize the effects of NPS on depression- and ...

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Item type:Article
Date:2012
Institutions:Biology, Preclinical Medicine > Institut für Zoologie > Tierphysiologie/Neurobiologie (Prof. Dr. Inga Neumann)
Identification Number:
ValueType
10.1017/S1461145711000678DOI
Keywords:Animal model, anxiety, gene expression, depression, NPS
Dewey Decimal Classification:500 Science > 570 Life sciences
500 Science > 590 Zoological sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:34579
Owner only: item control page

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