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Intrinsic and extrinsic determinants of central nervous system axon outgrowth into alginate-​based anisotropic hydrogels

Pawara, Kiran, Prang, Peter, Müller, Rainer, Caioni, Massimiliano, Bogdahn, Ulrich, Kunz, Werner and Weidner, Norbert (2015) Intrinsic and extrinsic determinants of central nervous system axon outgrowth into alginate-​based anisotropic hydrogels. Acta Biomaterialia 27, pp. 131-139.

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Abstract

Appropriate target reinnervation and functional recovery after spinal cord injury depend on longitudinally directed regrowth of injured axons. Anisotropic alginate-based capillary hydrogels (ACH) support peripheral nervous system derived axon growth, which is accompanied by glial supporting cell migration into the ACH. The aim of the present study was to analyze central nervous system (CNS) ...

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Item type:Article
Date:2015
Institutions:Medicine > Lehrstuhl für Neurologie
Chemistry and Pharmacy > Institut für Physikalische und Theoretische Chemie > Chair of Chemistry VI - Physical Chemistry (Solution Chemistry) > Prof. Dr. Werner Kunz
Identification Number:
ValueType
10.1016/j.actbio.2015.08.032DOI
Keywords:alginate gelatin hydrogel central nervous system axon outgrowth astrocyte
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:34598
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