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Molekulargenetische Untersuchungen zur systemischen Progression maligner Melanome

Hodak, Isabelle Rosa (2017) Molekulargenetische Untersuchungen zur systemischen Progression maligner Melanome. PhD, Universität Regensburg.

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Date of publication of this fulltext: 12 Jun 2017 05:39

Abstract (German)

Die Metastasierung des Melanoms in den ersten drainierenden Lymphknoten, den so genannten Wächterlymphknoten, beeinflusst das Überleben von Patienten mit klinisch lokalisierter Melanomerkrankung entscheidend (Balch et al., 2001; Ulmer et al., 2005). Der Prozess der Metastasierung, gerade in der frühen Phase, ist beim malignen Melanom noch unzureichend verstanden. Die Frage, auf welche Art frühe ...

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Translation of the abstract (English)

The metastasis of melanoma in the first draining lymph nodes (the sentinel lymph node) influences the survival of patients with clinically localized melanoma disease. The process of metastasis, especially in the early stage is still not understood. The question in what way early genomic changes of malignant cells can be identified, is therefore of great importance. The aim of this thesis was to ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:12 June 2017
Referee:Prof. Dr. Stephan Schneuwly
Date of exam:10 June 2016
Institutions:Medicine > Lehrstuhl für Pathologie
Medicine > Abteilung für Onkogenomik
Biology, Preclinical Medicine > Institut für Zoologie > Entwicklungsbiologie (Prof. Dr. Stephan Schneuwly)
Keywords:Malignes melanom, Disseminierung, Tumoreinzelzellen, CGH, SSCP, BRAF, NRAS, Cyclin D1
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:34634
Owner only: item control page

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