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Molecular dissection of the valproic acid effects on glioma cells

Riemenschneider, Markus J., Hoja, Sabine, Schulze, Markus, Rehli, Michael, Proescholdt, Martin A., Herold-Mende, Christl and Hau, Peter (2016) Molecular dissection of the valproic acid effects on glioma cells. Oncotarget 7 (39), pp. 62989-63002.

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Date of publication of this fulltext: 22 Nov 2016 10:10

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Other URL: http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=11379&pubmed-linkout=1


Abstract

Many glioblastoma patients suffer from seizures why they are treated with antiepileptic agents. Valproic acid (VPA) is a histone deacetylase inhibitor that apart from its anticonvulsive effects in some retrospective studies has been suggested to lead to a superior outcome of glioblastoma patients. However, the exact molecular effects of VPA treatment on glioblastoma cells have not yet been ...

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Item type:Article
Date:18 August 2016
Institutions:Medicine > Abteilung für Neuropathologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.18632/oncotarget.11379DOI
Keywords:brain cancer, glioblastoma, temozolomide, HDAC inhibitor, SLC transporter
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:34871
Owner only: item control page

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