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Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

Rebbeck, T. R., Mitra, N., Wan, F., Weber, Bernhard H. F. and et al., (2015) Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. JAMA 313, pp. 1347-1361.

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Abstract

IMPORTANCE: Limited information about the relationship between specific mutations in BRCA1 or BRCA2 (BRCA1/2) and cancer risk exists. OBJECTIVE: To identify mutation-specific cancer risks for carriers of BRCA1/2. DESIGN, SETTING, AND PARTICIPANTS: Observational study of women who were ascertained between 1937 and 2011 (median, 1999) and found to carry disease-associated BRCA1 or BRCA2 mutations. ...

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Item type:Article
Date:2015
Additional Information (public):Correction: This article was corrected online July 9, 2015, for an incorrectly labeled BRCA2 exon 11 in Figure 3. See JAMA. 2015 August 11; 314(6): 628
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1001/jama.2014.5985DOI
25849179PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:35138
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