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Genetic risk models in age-related macular degeneration

Grassmann, Felix, Heid, Iris M. and Weber, Bernhard H. F. (2014) Genetic risk models in age-related macular degeneration. In: Ash, J. and Grimm, C., (eds.) Retinal Degenerative Diseases. Advances in Experimental Medicine and Biology, 801. Springer, New York, NY, pp. 291-300. ISBN 978-1-4614-3209-8 (online), 978-1-4614-3208-1 (print).

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Abstract

Late-stage age-related macular degeneration (AMD) is a common sight-threatening disease of the central retina affecting approximately 1 in 30 Caucasians. Besides age and smoking, common genetic variants from at least 19 gene loci have reproducibly been associated with AMD likely explaining a large proportion of disease. Based on the current knowledge, several models were calculated to predict ...

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Item type:Book section
Date:2014
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1007/978-1-4614-3209-8_37DOI
24664710PubMed ID
Keywords:Age-related macular degeneration; Susceptibility; Logistic regression; Cox regression; Genetic risk score
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:35174
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