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Insulin-like growth factor II mRNA binding protein 3 (IMP3) is overexpressed in prostate cancer and correlates with higher Gleason scores

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Ikenberg, Kristian ; Fritzsche, Florian R. ; Zuerrer-Haerdi, Ursina ; Hofmann, Irina ; Hermanns, Thomas ; Seifert, Helge ; Müntener, Michael ; Provenzano, Maurizio ; Sulser, Tullio ; Behnke, Silvia ; Gerhardt, Josefine ; Mortezavi, Ashkan ; Wild, Peter ; Hofstädter, Ferdinand ; Burger, Maximilian ; Moch, Holger ; Kristiansen, Glen
License: Creative Commons: Attribution 3.0
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Date of publication of this fulltext: 09 Feb 2017 13:15


Background The oncofetal protein insulin-like growth factor II mRNA binding protein 3 (IMP3) is an important factor for cell-migration and adhesion in malignancies. Recent studies have shown a remarkable overexpression of IMP3 in different human malignant neoplasms and also revealed it as an important prognostic marker in some tumor entities. To our knowledge, IMP3 expression has not been ...


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