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Docosahexaenoic acid attenuates microglial activation and delays early retinal degeneration

Ebert, Stefanie, Weigelt, K., Walczak, Yana, Drobnik, W., Mauerer, Richard, Hume, David A. and Weber, Bernhard H. F. (2009) Docosahexaenoic acid attenuates microglial activation and delays early retinal degeneration. Journal of Neurochemistry 110, pp. 1863-1875.

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Abstract

Microgliosis is a common phenomenon in neurodegenerative disorders including retinal dystrophies. We performed a detailed characterization of activated microglia in the retinoschisin (Rs1h)-deficient (Rs1h(-/Y)) mouse model of inherited retinal degeneration. To visualize and isolate microglia, we crossed Rs1h(-/Y) animals with transgenic MacGreen mice, which express green fluorescent protein ...

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Item type:Article
Date:2009
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1111/j.1471-4159.2009.06286.xDOI
19627444PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35202
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