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Chondroitin sulfate disaccharide stimulates microglia to adopt a novel regulatory phenotype

Ebert, Stefanie, Schoeberl, Tobias, Walczak, Yana, Stoecker, Katharina, Stempfl, Thomas, Moehle, Christoph, Weber, Bernhard H. F. and Langmann, Thomas (2008) Chondroitin sulfate disaccharide stimulates microglia to adopt a novel regulatory phenotype. Journal of Leukocyte Biology 84, pp. 736-740.

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Abstract

A disaccharide degradation product of chondrotin sulfate proteoglycan-disaccharide (CSPG-DS) has been implicated previously in the inhibition of neurodegeneration by influencing microglia activation. In this study, genome-wide microarray analysis was used to identify specific gene expression profiles of CSPG-DS-stimulated BV-2 microglia-like cells. Gene products involved in phagocytosis, ...

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Item type:Article
Date:2008
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1189/jlb.0208138DOI
18550791PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35214
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