Go to content
UR Home

Effect of Late-stage Therapy on Disease Progression in AAV-mediated Rescue of Photoreceptor Cells in the Retinoschisin-deficient Mouse

URN to cite this document:
urn:nbn:de:bvb:355-epub-352220
DOI to cite this document:
10.5283/epub.35222
Janssen, A. ; Min, S. H. ; Molday, L. . ; Tanimoto, N. ; Seeliger, N. W. ; Hauswirth, W. W. ; Molday, R. S. ; Weber, Bernhard H. F.
[img]
Preview
License: Creative Commons Attribution 4.0
PDF - Published Version
(2MB)
Date of publication of this fulltext: 14 Feb 2017 12:24


Abstract

Proof-of-concept for a successful adeno-associated virus serotype 5 (AAV5)-mediated gene therapy in X-linked juvenile retinoschisis (XLRS) has been demonstrated in an established mouse model for this condition. The initial studies concentrated on early time-points of treatment. In this study, we aimed to explore the consequences of single subretinal injections administered at various stages of ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons