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A low copy repeat located in subtelomeric regions of 14 different human chromosomal termini

Weber, Bernhard H. F. , Allen, L, Magenis, R E and Hayden, M R (1991) A low copy repeat located in subtelomeric regions of 14 different human chromosomal termini. Cytogenetics and cell genetics 57 (4), pp. 179-183.

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Abstract

Two cosmid clones, cG1A3 and cG1A6, containing large blocks of a telomeric repeat sequence, (TTAGGG)n, were isolated independently. Restriction mapping and fingerprinting studies suggested that cosmid cG1A6 is entirely contained within cG1A3. Competitive in situ hybridization localized cG1A3 to 14 different human telomeres and one internal site at 2q14→q21, indicating the presence of a subtelomeric low-copy repeat within this cosmid.


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Item type:Article
Date:1991
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1159/000133141DOI
1743071PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:35280
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