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Non-random association between alleles detected at D4S95 and D4S98 and the Huntington's disease gene

Theilmann, J. ; Kanani, S. ; Shiang, R. ; Robbins, C. ; Quarrell, O. ; Huggins, M. ; Hedrick, A. ; Weber, Bernhard H. F. ; Collins, C. ; Wasmuth, J. J. ; Buetow, K. H. ; Murray, J. C. ; Hayden, M. R.



Abstract

Analysis of many families with linked DNA markers has provided support for the Huntington's disease (HD) gene being close to the telomere on the short arm of chromosome 4. However, analysis of recombination events in particular families has provided conflicting results about the precise location of the HD gene relative to these closely linked DNA markers. Here we report an investigation of ...

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