Go to content
UR Home

A Sequence-Ready High-Resolution Physical Map of the Best Macular Dystrophy Gene Region in 11q12–q13

Cooper, P. ; Nowak, N. J. ; Higgins, M. J. ; Simpson, S. A. ; Stöhr, H. ; Marquardt, A. ; Weber, Bernhard H. F. ; Gerhard, D. S. ; de Jong, P. J. ; Shows, T. B.


Best disease, an autosomal dominant inherited macular degenerative disorder, was previously localized between D11S1765 and UGB (uteroglobin) in 11q13 by genetic linkage analysis. Since this region was found to be refractory to cloning in YAC (yeast artificial chromosome)-based vectors, a P1 artificial chromosome (PAC) contig was assembled. Gridded PAC libraries representing a 16-fold genome ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: daten@ur.de
0941 943 -5707

Contact persons