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Identification of a DMBT1 polymorphism associated with increased breast cancer risk and decreased promoter activity

Tchatchou, S, Riedel, A, Lyer, S, Schmutzhard, J, Strobel-Freidekind, O, Gronert-Sum, S, Mietag, C, D'Amato, M, Schlehe, B, Hemminki, K, Sutter, C, Ditsch, N, Blackburn, A, Hill, L Z, Jerry, D J, Bugert, P, Weber, Bernhard H. F. and et al, . (2010) Identification of a DMBT1 polymorphism associated with increased breast cancer risk and decreased promoter activity. Human Mutation 31 (1), pp. 60-66.

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Abstract

According to present estimations, the unfavorable combination of alleles with low penetrance but high prevalence in the population might account for the major part of hereditary breast cancer risk. Deleted in Malignant Brain Tumors 1 (DMBT1) has been proposed as a tumor suppressor for breast cancer and other cancer types. Genomewide mapping in mice further identified Dmbt1 as a potential ...

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Item type:Article
Date:2010
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1002/humu.21134DOI
19830809PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:35455
Owner only: item control page
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