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Evidence of association of APOE with age-related macular degeneration - a pooled analysis of 15 studies

McKay, G J, Patterson, C C, Chakravarthy, U, Dasari, S, Klaver, C C, Vingerling, J R, Ho, L, De Jong, P T, Fletcher, A E, Young, I S, Seland, J H, Rahu, M, Soubrane, G, Tomazzoli, L, Topouzis, F, Vioque, J, Weber, Bernhard H. F. and et al, . (2011) Evidence of association of APOE with age-related macular degeneration - a pooled analysis of 15 studies. Human Mutation 32 (12), pp. 1407-1416.

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Abstract

Age-related macular degeneration (AMD) is the most common cause of incurable visual impairment in high-income countries. Previous studies report inconsistent associations between AMD and apolipoprotein E (APOE), a lipid transport protein involved in low-density cholesterol modulation. Potential interaction between APOE and sex, and smoking status has been reported. We present a pooled analysis (n ...

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Item type:Article
Date:2011
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1002/humu.21577DOI
21882290PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:35456
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