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Tapping Stem Cells to Target AMD: Challenges and Prospects

Brandl, Caroline, Grassmann, Felix, Riolfi, Julia and Weber, Bernhard H. F. (2015) Tapping Stem Cells to Target AMD: Challenges and Prospects. Journal of Clinical Medicine 4, pp. 282-303.

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Date of publication of this fulltext: 04 Apr 2017 08:56

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Abstract

Human pluripotent stem cells (hPSCs) are increasingly gaining attention in biomedicine as valuable resources to establish patient-derived cell culture models of the cell type known to express the primary pathology. The idea of "a patient in a dish" aims at basic, but also clinical, applications with the promise to mimic individual genetic and metabolic complexities barely reflected in current ...

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Item type:Article
Date:2015
Institutions:Medicine > Lehrstuhl für Augenheilkunde
Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.3390/jcm4020282DOI
26239128PubMed ID
Keywords:RNA-sequencing; age-related macular degeneration (AMD); cell-based transplantation therapy; disease modelling; drug screening; induced pluripotent stem cells (iPSCs); retinal pigment epithelium (RPE); stem cells
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35518
Owner only: item control page

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