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In-Depth Functional Diagnostics of Mouse Models by Single-Flash and Flicker Electroretinograms without Adapting Background Illumination

Tanimoto, Naoyuki, Michalakis, S., Weber, Bernhard H. F. , Wahl-Schott, C. A., Hammes, Hans-Peter and Seeliger, Mathias W. (2016) In-Depth Functional Diagnostics of Mouse Models by Single-Flash and Flicker Electroretinograms without Adapting Background Illumination. In: Bowes Rickman, C., (ed.) Retinal Degenerative Diseases. Advances in Experimental Medicine and Biology, 854. Springer International Publishing, Cham, Switzerland, pp. 619-625. ISBN 978-3-319-17120-3.

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Abstract

Electroretinograms (ERGs) are commonly recorded at the cornea for an assessment of the functional status of the retina in mouse models. Full-field ERGs can be elicited by single-flash as well as flicker light stimulation although in most laboratories flicker ERGs are recorded much less frequently than singleflash ERGs. Whereas conventional single-flash ERGs contain information about layers, i.e., ...

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Item type:Book section
Date:2016
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1007/978-3-319-17121-0_82DOI
26427467PubMed ID
Keywords:Congenital stationary night blindness; Electroretinogram; Flicker; Functional diagnostics; Mouse model; Photoreceptor; Retinal bipolar cell; Retinal ischemia; Single-flash; X-linked juvenile retinoschisis
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35522
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