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Agonists and knockdown of estrogen receptor β differentially affect invasion of triple-negative breast cancer cells in vitro

URN to cite this document:
urn:nbn:de:bvb:355-epub-355421
DOI to cite this document:
10.5283/epub.35542
Schüler-Toprak, Susanne ; Häring, Julia ; Inwald, Elisabeth C. ; Moehle, Christoph ; Ortmann, Olaf ; Treeck, Oliver
Date of publication of this fulltext: 19 Apr 2017 11:03


Abstract

Background: Estrogen receptor beta (ER beta) is expressed in the majority of invasive breast cancer cases, irrespective of their subtype, including triple-negative breast cancer (TNBC). Thus, ER beta might be a potential target for therapy of this challenging cancer type. In this in vitro study, we examined the role of ER beta in invasion of two triple-negative breast cancer cell lines. Methods: ...

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