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Structural and functional characterization of the RNA-binding proteins Loquacious and Brain tumor from Drosophila melanogaster

Jakob, Leonhard (2017) Structural and functional characterization of the RNA-binding proteins Loquacious and Brain tumor from Drosophila melanogaster. PhD, Universität Regensburg.

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Date of publication of this fulltext: 12 Apr 2017 11:43

Abstract (German)

Die post-transkriptionelle Regulation spielt eine wichtige Rolle bei der Gen-Expression in Pro- und Eukaryoten und erlaubt eine rasche Anpassung an eine sich stets verändernde Umgebung. Dabei sind RNA-bindende Proteine von zentraler Bedeutung, indem sie mit der „messenger RNA“ (mRNA) interagieren und dabei ihre Reifung, Lokalisierung, Translation und ihren Abbau regulieren. Um ihre Ziel-Sequenzen ...

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Translation of the abstract (English)

Post-transcriptional gene regulation (PTGR) processes play a major role in eukaryotic and prokaryotic gene expression and mainly act on the mRNA level. Therefore, among other cellular processes, PTGR allows cells to react on constantly changing environmental influences, by the ability to rapidly adjust internal protein levels. As key players in such regulatory processes, RNA-binding proteins ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:12 April 2017
Referee:Prof. Dr. Gunter Meister
Date of exam:15 March 2017
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I > Prof. Dr. Gunter Meister
Keywords:Dicer, Loquacious, Ago, Brat, Drosophila, Post-transcriptional gene regulation, FCCS, Single molecule pulldown
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35553
Owner only: item control page

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