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Photochromic Dopamine Receptor Ligands Based on
Dithienylethenes and Fulgides

Lachmann, Daniel, Studte, Carolin, Männel, Barbara, Hübner, Harald, Gmeiner, Peter and König, Burkhard (2017) Photochromic Dopamine Receptor Ligands Based on
Dithienylethenes and Fulgides.
Chemistry - A European Journal 23, pp. 13423-13434.

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Abstract

We describe the incorporation of the well-investigated class of photochromic dithienylethenes (DTEs) and fulgides into known dopamine receptor ligands such as 1,4-disubstituted aromatic and hydroxybenzoxazinone piperazines as well as aminoindanes. Subtype and functional selective photochromic ligands were obtained and characterized by NMR and UV/VIS spectroscopic measurements. The photophysical ...

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Item type:Article
Date:2017
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:GRK 1910, Graduiertenkolleg "Medicinal Chemistry of Selective GPCR Ligands"
Identification Number:
ValueType
10.1002/chem.201702147DOI
Keywords:BY-PRODUCT FORMATION; OPTICAL CONTROL; DIARYLETHENE DERIVATIVES; MOLECULAR SWITCHES; PARTIAL AGONISTS; DRUG DISCOVERY; IN-VIVO; LIGHT; INHIBITORS; DESIGN; dithienylethene; dopamine; fulgimide; gpcr; photoswitch
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:35795
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