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Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population

Meindl, A, Weber, Bernhard H. F. and German Consortium for Hereditary Breast and Ovarian Cancer, . (2002) Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population. International Journal of Cancer 97 (4), pp. 472-480.

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Abstract

The main focus of this German-wide multi-center study was to establish a BRCA1/2 mutation profile and to determine family types with high frequencies of mutations in these genes. In a comprehensive study, the entire coding sequences of the breast cancer genes BRCA1 and BRCA2 were analyzed in 989 unrelated patients from German breast/ovarian cancer families. A total of 77 BRCA1 and 63 BRCA2 ...

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Item type:Article
Date:2002
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1002/ijc.1626DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:35822
Owner only: item control page
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