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Systemic complement activation in age-related macular degeneration

Scholl, H P, Charbel Issa, P, Walier, M, Janzer, S, Pollok-Kopp, B, Börncke, F, Fritsche, L G, Chong, N V, Fimmers, R, Wienker, T, Holz, F G, Weber, Bernhard H. F. and Oppermann, M (2008) Systemic complement activation in age-related macular degeneration. PLoS one 3 (7), e2593.

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Date of publication of this fulltext: 07 Jul 2017 11:41

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Other URL: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0002593


Abstract

Dysregulation of the alternative pathway (AP) of complement cascade has been implicated in the pathogenesis of age-related macular degeneration (AMD), the leading cause of blindness in the elderly. To further test the hypothesis that defective control of complement activation underlies AMD, parameters of complement activation in blood plasma were determined together with disease-associated ...

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Item type:Article
Date:2008
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1371/journal.pone.0002593DOI
18596911PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:35849
Owner only: item control page

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