Membrane-associated guanylate kinase proteins MPP4 and MPP5 associate with Veli3 at distinct intercellular junctions of the neurosensory retina

URN to cite this document:: urn:nbn:de:bvb:355-epub-359172
DOI to cite this document:: 10.5283/epub.35917

Stöhr, H. ; Molday, L. L. ; Molday, R. S. ; Weber, Bernhard H. F.

; Biedermann, B. ; Reichenbach, A. ; Krämer, F.

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Date of publication of this fulltext: 28 Jul 2017 08:41

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Abstract

MPP4 and MPP5 are closely related members of the p55-subfamily of membrane-associated guanylate kinases (MAGUKs) known to mediate the assembly of protein complexes at the plasma membrane of cell–cell junctions. Both MPP4 and MPP5 have been implicated in retinal function; however, their specific roles in the cellular mechanisms underlying vision are largely unknown. Here, we generated specific ...