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Variations in five genes and the severity of age-related macular degeneration: - results from the Muenster aging and retina study

Farwick, A, Dasch, B, Weber, Bernhard H. F. , Pauleikhoff, D, Stoll, M and Hense, H W (2009) Variations in five genes and the severity of age-related macular degeneration: - results from the Muenster aging and retina study. Eye (Lond) 23 (12), pp. 2238-2244.

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Abstract

Aims Little is known about the role of genetic variants in the early stages of age-related macular degeneration (AMD). We aimed to investigate how genetic variations within five well-defined genes relate to AMD severity. Methods We analysed SNPs in the genes for complement factor H (CFH), age-related maculopathy susceptibility (ARMS2), HtrA serine peptidase 1 (HtrA1), complement factor B ...

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Item type:Article
Date:2009
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1038/eye.2008.426DOI
19169232PubMed ID
Keywords:age-related macular degeneration, severity, CFH, ARMS2, HtrA1, C2, CFB
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:35980
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