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Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people

McKay, G. J., Silvestri, G., Chakravarthy, U., Dasari, S., Fritsche, L. G., Weber, Bernhard H. F. and et al, . (2011) Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people. American Journal of Epidemiology 173 (12), pp. 1357-1364.

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Other URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145394/


Abstract

Variation in the apolipoprotein E gene (APOE) has been reported to be associated with longevity in humans. The authors assessed the allelic distribution of APOE isoforms ε2, ε3, and ε4 among 10,623 participants from 15 case-control and cohort studies of age-related macular degeneration (AMD) in populations of European ancestry (study dates ranged from 1990 to 2009). The authors included only the ...

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Item type:Article
Date:2011
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1093/aje/kwr015DOI
21498624PubMed ID
Keywords:aged, apolipoprotein E2, apolipoprotein E3, apolipoprotein E4, apolipoproteins E, longevity, meta-analysis, multicenter study
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:36025
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