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Tenomodulin is Required for Tendon Endurance Running and Collagen I Fibril Adaptation to Mechanical Load

Dex, Sarah, Alberton, Paolo, Willkomm, Lena, Söllradl, Thomas, Bago, Sandra, Milz, Stefan, Shakibaei, Mehdi, Ignatius, Anita , Bloch, Wilhelm, Clausen-Schaumann, Hauke , Shukunami, Chisa, Schieker, Matthias and Docheva, Denitsa (2017) Tenomodulin is Required for Tendon Endurance Running and Collagen I Fibril Adaptation to Mechanical Load. EBioMedicine 2017 (20), pp. 240-254.

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Date of publication of this fulltext: 04 Sep 2017 09:10

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Other URL: http://www.sciencedirect.com/science/article/pii/S2352396417301949?via%3Dihub

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

Tendons are dense connective tissues that attach muscles to bone with an indispensable role in locomotion because of their intrinsic properties of storing and releasing muscle-generated elastic energy. Tenomodulin (Tnmd) is a well-accepted gene marker for the mature tendon/ligament lineage and its loss-of -function in mice leads to a phenotype with distinct signs of premature aging on tissue and ...

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Item type:Article
Date:5 May 2017
Institutions:Medicine > Lehrstuhl für Unfallchirurgie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1016/j.ebiom.2017.05.003DOI
Article 56 (1) (k)Other
Keywords:ATOMIC-FORCE MICROSCOPY; HUMAN ACHILLES-TENDON; STEM/PROGENITOR CELLS; SKELETAL-MUSCLE; CHONDROMODULIN-I; BIOMECHANICAL PROPERTIES; PERIODONTAL-LIGAMENT; ELASTIC PROPERTIES; CONNECTIVE-TISSUE; STEM-CELLS; Tendons; Tenomodulin; Knockout mouse model; Running tests; Atomic force microscopy; Collagen I crosslinking
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36050
Owner only: item control page

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