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Amelioration of portal hypertension and the hyperdynamic circulatory syndrome in cirrhotic rats by neuropeptide Y via pronounced splanchnic vasoaction

Moleda, Lukas, Trebicka, J., Dietrich, Peter, Gäbele, Erwin, Hellerbrand, Claus , Straub, Rainer H. , Sauerbruch, T., Schölmerich, Jürgen and Wiest, Reiner (2011) Amelioration of portal hypertension and the hyperdynamic circulatory syndrome in cirrhotic rats by neuropeptide Y via pronounced splanchnic vasoaction. Gut 60, pp. 1122-1132.

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Abstract

Background: Splanchnic vasodilation triggers the development of the hyperdynamic circulatory syndrome in portal hypertension. Neuropeptide Y (NPY), a sympathetic co-transmitter of norepinephrine, improves contractility in mesenteric arteries of pre-hepatic portal hypertensive rats. Therefore, we investigated the effect of NPY on mesenteric arterial contractility in vitro and in vivo in cirrhotic ...

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Item type:Article
Date:2011
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1136/gut.2010.226407DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:36125
Owner only: item control page

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